Hylase Dessau®, hyaluronidase, is an enzyme which dissolves BDDE-bound hyluronan gel (so-called hyaluronic acid for cosmetic injections) to a non-viscous (aqueous) liquid. The hyaluronic acid dissolved after a hylase injection can now be removed from the tissue via the lymphatic system. Hyaluronic acid dissolved in water can be pressed out of the previously 'occupied' compartment with the fingers, but usually flows back there immediately. Hylase works immediately. The removal may take some time. Not only freshly injected hyaluronic acid, but also relative swellings or bulges that already exist years after a hyaluronic acid injection can be dissolved with hyaluronidase (hylase).
This tradition should not be overestimated. The body's own hyaluronic acid is subject to a continuous cycle of production and degradation. Hylase should be used carefully to aesthetically improve a disfiguring bulge or a resulting swelling. In practice, the degradation of the body's own hyaluronic acid by hylase plays no role.
After a delivery, the previously tensed and now relieved abdominal skin shows a less smooth surface than before. This is also the case with the successful therapy of a long-standing swelling in the face after a hyaluronic acid injection. It is certainly aesthetically more correct to relieve a disfiguring swelling with overlying tense skin and accept the normal recurring wrinkle pattern than to leave the swelling untreated. Many swellings after an injection must be given a certain period of time (max. 14 days) to improve spontaneously. After that, however, waiting should be replaced by active therapy.
Here the experience of the users varies greatly. In our practices we use small doses of Hylase. If necessary, we proceed in several steps to dissolve unwanted hyaluronic acid swellings or bulges.
If acute ischemia occurs during a hyaluronic acid injection, this is an emergency. Especially in case of a functional impairment due to this circulatory disorder, Hylase should be injected immediately. Ideally, this can be done through the still placed injection cannula. Hylase belongs in every refrigerator of an injection practice and should also not be missing at so-called injection workshops.